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Advanced Retino-Mela Serum

#ANTI-AGING
#SKIN TURNOVER
#BEGINNER-FRIENDLY

A gentle corrective serum formulated with retinol, a gold-standard ingredient known for improving skin turnover. Helps reduce uneven tone, smooth texture, and soften the look of fine lines without harsh irritation.

Regular price $35.90
Sale price $35.90 Regular price $49.00
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Advanced Retino-Mela Serum

Advanced Retino-Mela Serum

Regular price $35.90
Sale price $35.90 Regular price $49.00
Unit price
[SKIN TURNOVER · ANTI-AGING]

Advanced Retino-Mela Serum

A next-generation retinoid with 30x greater stability than retinol, delivering higher efficacy with reduced irritation.

Surface Renewal

HPR accelerates skin turnover for smoother, brighter texture

Block Melanin Transfer

Niacinamide 10% stops melanin from reaching skin surface

Control Production

TXA 4% + α-Bisabolol block melanin at the source

Free from 82+ Harmful Substances

Dr. Reju-All excludes parabens, sulfates, phthalates, and 80+ additional substances on global regulatory exclusion lists. Manufactured to pharmaceutical-grade quality standards.

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Frequently Asked Questions

What is "The Next Generation Retinoid"?

How does Retino-Mela Serum control melanin?

How do I use Retino-Mela Serum?

Can I use retinoid products during pregnancy?

What age is appropriate for retinoid products?

Is Retino-Mela Serum tested for irritation?

Customers praised this retinol serum for its lightweight, non-greasy texture that absorbs quickly and "works great" on skin. Many noted improved hydration, firmness, and "healthy glow" with reduced redness and pores. Results are gradual but effective for evening skin tone and fading dark spots. Some found it pricey compared to other Korean skincare.

Skin (positive)Pores (positive)Makeup (positive)Pigmentation (positive)Texture (positive)
  • 5 stars: 13 (72%)
  • 4 stars: 5 (28%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
D
D.

Works Great

A
A.

I’ve been using this face serum for a few weeks now, and I’m honestly impressed. It absorbs quickly, doesn’t feel greasy, and my skin looks more hydrated and smooth. I’ve noticed a real difference in my complexion — less redness and a nice, healthy glow. Definitely a great product. Highly recommended!

S
S.

Love it

A
A.C.

I'm very happy with my product; it arrived earlier than expected. I'll be incorporating it into my skincare routine recommended by my dermatologist. 🤎

S
S.M.

Use the entire routine on my skin every morning. Works really well under makeup as a great base on mature skin.

C
C.L.
Contains legit ingredients

This serum contains Hydroxypinacolone Retinoate, Niacinamide, and Tranexamic Acid. Most good face serums include at least one of them. This has three. This feels and works very well on the skin. It's not too sticky or and goes on well. My skin is firmer and looks a lot heathier.

D
D.D.
Retinol Alternative Serum for Pore and Tone Support

This serum is designed as part of a Korean skincare routine with a focus on anti-aging and tone-care support. It features next-generation HPR retinol, which is described as gentler and more stable than traditional forms, making it beginner-friendly. The intended purpose is to help minimize the look of pores, refine texture, and support a smoother, firmer appearance to the skin. The formula also includes Niacinamide (10%) and Tranexamic Acid (TXA, 4%), both commonly used for tone correction and helping to reduce the appearance of dark spots and unevenness. Together with Alpha-Bisabolol, these ingredients are meant to support what the description calls “melanin triple care” for blocking, preventing, and clearing uneven pigmentation. Dermatological testing is mentioned for sensitive users, as it is labeled non-comedogenic and free from artificial color and fragrance. The serum is naturally scented from 99% pure PDRN and claims to have received an “excellent” rating from Dermatest in Germany for skin compatibility. The recommended use is after toner and before cream in the evening routine. If used in the morning, it should be followed by sunscreen. Overall, this product is positioned as a gentle, structured step for targeting visible signs of aging and uneven tone, developed by doctors and pharmacists and already popular in Korean pharmacies. Good value here for a carefully formulated skincare item.

F
F.
Gentle, Effective Serum with Gradual Results

This serum has been a solid addition to my nighttime routine. The texture is lightweight and absorbs quickly without any stickiness, and I didn’t experience irritation, which is rare for me with retinoids. After a few weeks, my skin looked a bit smoother and more even-toned, especially around the pores. The brightening effect is gradual but noticeable. It’s not a miracle product, but for a gentle retinoid with added benefits, it holds its own. Definitely feels like a step up from basic retinol serums.

C
C.r.
No MAKEUP!!

Best way to achieve glass skin. My skin was a wreck after a laser and it still looked ok after only applying this cream. Only product I want to use. Period.This photo was after applying the barrier cream in the morning ONLY, working all day, chasing around 2 kids, and doing nothing else to my face.

m
m.
Wow overnight difference

There are not many skincare products that make a difference overnight but this one did for me. It wasn't a complete overhaul but noticeable. The biggest difference I see using this is increased hydration and an improvement in skin appearance (wrinkles, appearance of pore size, and more radiant, but not greasy). The texture is like a gel and I like the tube packaging. It contains 1200 ppm of medical grade PDRN which is supposed to be the optimal level for skin. I've also put this on my lips if there are really dry under aquaphor and it speeds up the healing process. I have never broken out from this and it feels nice on the skin. I'm knocking off a star because compared to other Korean skincare I've used, this is more expensive on a ml/dollar. Granted it is a product that is sold in pharmacies so I think the ingredients in here are higher in quality. I'm not sure how much a tube will last but if I can get at least a month out of it, the price will be worth it for me.

J
J.R.
Dream cream

Excellent, makes your skin feel incredibly soft and absorbs right in, without feeling greasy or leaving your face feeling anything but fresh and bouncy.

J
J.
Love this magic serum

This stuff is fantastic! My skin is hydrated and soft with no greasy residue, and it sinks right in so it works well under makeup. So glad I bought this.

S
S.
Not bad.. still trying it out

I’ve been using this for a couple weeks now, on and off, and I will say that it does help even out my skin. Not in a dramatic way or anything, but I do notice my skin has less.. different areas of coloration if that makes sense? Like it brings down the intensity of the dark circles of my eyes, or the dry patches around my face. It’s like.. very low grade and non-skin harming concealer. I use it under Aveeno SPF daily moisturizer and my skin looks great. Not flawless but does have a slight glow to it. The quality feels nice. I’ve never heard of this brand before but I am open to exploring other products. Not much smell, glides easily, is surprisingly hydrating by itself, and seems to be doing something.

T
T.
Wonderful product with great results

This Reju-All Advanced Retino-Mela Serum is amazing. I have only used this a couple of days now and my skin feels so soft and smooth. I have had adverse reactions to this at all which is pretty amazing in itself being that I have rosacea and can use very few products that don't cause irritation and an outbreak. My skin feels tighter as well. I am anxious to see the results after a couple of weeks. The pump style application is very nice and a little bit goes a long way so this bottle will last quite a while. I would definitely recommend this and feel this is well worth the cost for the fantastic results.

V
V.b.
Well rounded anti aging, dark spot fading, brightening serum!

This is a great and well known Korean brand that is sold in Korean pharmacies. I have their PDRN gel cream and enjoy it.The formulation of this product is awesome and the price is really decent. It features HPR 0.1%, a retinol that is more stable and gentle while being highly effective. This will provide anti-aging factors. I love that this is paired with tranexamic 4% to help with fading dark spots and Niacinamide 10%, which helps brighten the complexion, hydrate, control sebum, and provide anti-aging support. The combination of these three main ingredients makes it perfect to actually replace other products in my routine.Included are other solid skin goodie ingredients like squalane+bisabolol (helps balance dryness that retinol may cause), botanical extracts, multiple ferments, HA, panthenol and betaine. It's a very well rounded serum that provides a lot of different benefits all in one. It's awesome there are no added fragrances which can be a potential skin irritant for some.If you're new to retinol and want to start easy while still seeing results, this is definitely worth a try!

s
s.
Subtle Difference so far using Advanced Retino-Mela Serum 1 Fl Oz

I have more noticeable hyperpigmentation during the summer months and wanted to see if this would make any difference in making it less noticeable. This is a 1 oz bottle of Retinol serum has ingredients specifically for blocking melanin and improving uneven complexion.This serum is thin, spreads easily, and absorbs quickly. I usually apply it at night time since it is sensitive to the sun. So far, I haven’t noticed anything drastic to the areas I have applied it to on my face. If anything, a subtle difference in fading those spots. Hopefully, with longer use, I will see more improvement.Overall, the quality is good and the price could be less for the value of this product.

u
u.
Long lasting hydration without heavy feel

This cream has been great so far. I can really feel the hydration lasting after I apply it, but it doesn’t feel heavy at all, which makes it perfect for daily use. The tube is light enough to carry around and reapply during the day if needed. Also, there’s no strong scent, which I personally prefer. Overall, I’m quite happy with it!

C
C.
I like this product a lot!

I have allowed my tretinoin prescription to lapse for several months now, and I finally got the prescription refilled. I am reluctant to start the process of using it all over because it does take some time and commitment to allow the skin to adjust to the harshness of the product. The skin barrier can become compromised, and there is a lot of peeling, sometimes for months. I decided to start very, very slow, using it only once a week, and to use this product on the days that I am not using the other product.Well, I am finding that I love this serum! A lot. I think there is a synergistic blend of the retinol, with the Tranexamic Acid and the niacinamide. It is really helping to diminish the hyperpigmentation area I have on my forehead. I also think the synergy continues with the squalene, keeping the formulation from being too harsh for the skin. I use tretinoin primarily for anti aging benefits and cell turnover, but I have never found it to do a tremendous amount for my area of hyperpigmentation. This works for that concern very well,a nd I am going to continue to use this product. I thought it would be just to help wit the adjustment period of the other product, but I want to continue using it as a stand alone product in my skincare.