Advanced Retino-Mela Serum

This serum contains Hydroxypinacolone Retinoate, Niacinamide, and Tranexamic Acid. Most good face serums include at least one of them. This has three. This feels and works very well on the skin. It's not too sticky or and goes on well. My skin is firmer and looks a lot heathier.

This serum is designed as part of a Korean skincare routine with a focus on anti-aging and tone-care support. It features next-generation HPR retinol, which is described as gentler and more stable than traditional forms, making it beginner-friendly. The intended purpose is to help minimize the look of pores, refine texture, and support a smoother, firmer appearance to the skin. The formula also includes Niacinamide (10%) and Tranexamic Acid (TXA, 4%), both commonly used for tone correction and helping to reduce the appearance of dark spots and unevenness. Together with Alpha-Bisabolol, these ingredients are meant to support what the description calls “melanin triple care” for blocking, preventing, and clearing uneven pigmentation. Dermatological testing is mentioned for sensitive users, as it is labeled non-comedogenic and free from artificial color and fragrance. The serum is naturally scented from 99% pure PDRN and claims to have received an “excellent” rating from Dermatest in Germany for skin compatibility. The recommended use is after toner and before cream in the evening routine. If used in the morning, it should be followed by sunscreen. Overall, this product is positioned as a gentle, structured step for targeting visible signs of aging and uneven tone, developed by doctors and pharmacists and already popular in Korean pharmacies. Good value here for a carefully formulated skincare item.

This serum has been a solid addition to my nighttime routine. The texture is lightweight and absorbs quickly without any stickiness, and I didn’t experience irritation, which is rare for me with retinoids. After a few weeks, my skin looked a bit smoother and more even-toned, especially around the pores. The brightening effect is gradual but noticeable. It’s not a miracle product, but for a gentle retinoid with added benefits, it holds its own. Definitely feels like a step up from basic retinol serums.

Best way to achieve glass skin. My skin was a wreck after a laser and it still looked ok after only applying this cream. Only product I want to use. Period.This photo was after applying the barrier cream in the morning ONLY, working all day, chasing around 2 kids, and doing nothing else to my face.

There are not many skincare products that make a difference overnight but this one did for me. It wasn't a complete overhaul but noticeable. The biggest difference I see using this is increased hydration and an improvement in skin appearance (wrinkles, appearance of pore size, and more radiant, but not greasy). The texture is like a gel and I like the tube packaging. It contains 1200 ppm of medical grade PDRN which is supposed to be the optimal level for skin. I've also put this on my lips if there are really dry under aquaphor and it speeds up the healing process. I have never broken out from this and it feels nice on the skin. I'm knocking off a star because compared to other Korean skincare I've used, this is more expensive on a ml/dollar. Granted it is a product that is sold in pharmacies so I think the ingredients in here are higher in quality. I'm not sure how much a tube will last but if I can get at least a month out of it, the price will be worth it for me.